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Semaglutide activates GLP-1 receptors throughout the brain, including mood-regulating areas, so some temporary emotional changes are physiologically plausible
In many patients, we prescribe semaglutide or tirzepatide long term at lower doses, not just for weight management, but for metabolic effects and as a tool to counteract aging-related decline
Gestational weight gain and pregnancy outcomes after GLP-1 receptor agonist discontinuation
Adv Pharmacol Sci 2016:9463476 Sung MJ, Kim D-H, Davaatseren M, Hur HJ, Kim W, Jung YJ, Park SK, Kwon DY (2010) Genistein suppression ofTNF-alpha-induced fractalkine expression in endothelial cells
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